|
Christian Boehmer Anfinsen, Jr. (March 26, 1916 – May 14, 1995) was an American biochemist. He shared the 1972 Nobel Prize in Chemistry with Stanford Moore and William Howard Stein for work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation (see Anfinsen's dogma).〔(''The Nobel Prize in Chemistry 1972'' (The Royal Swedish Academy of Sciences) ). Nobelprize.org. Retrieved on 2012-03-08.〕 ==Background== Anfinsen was born in Monessen, Pennsylvania, into a family of Norwegian American immigrants. His parents were Sophie (Rasmussen) and Christian Boehmer Anfinsen, Sr., a mechanical engineer.〔https://profiles.nlm.nih.gov/ps/retrieve/Narrative/KK/p-nid/14〕 The family moved to Philadelphia in the 1920s. He earned a bachelor's degree from Swarthmore College in 1937. While attending Swarthmore College he played varsity football and joined the Delta Upsilon Fraternity. In 1939, he earned a master's degree in organic chemistry from the University of Pennsylvania. In 1939, The American-Scandinavian Foundation awarded Anfinsen a fellowship to develop new methods for analyzing the chemical structure of complex proteins, namely enzymes, at the Carlsberg Laboratory in Copenhagen, Denmark. In 1941, Anfinsen was offered a university fellowship for doctoral study in the Department of Biological Chemistry at Harvard Medical School. There, Anfinsen received his Ph.D. in biochemistry in 1943.〔(''Biography of Christian B. Anfinsen'' (U.S. National Library of Medicine) ). Profiles.nlm.nih.gov. Retrieved on 2012-03-08.〕 In 1979, he converted to Judaism, by undergoing an Orthodox conversion and that same year he quit smoking. Although Anfinsen wrote in 1985 that his feelings on religion still reflect a fifty-year period of orthodox agnosticism.〔(【引用サイトリンク】title=''The Christian B. Anfinsen Papers'' )〕 Anfinsen had three children with his first wife, Florence Kenenger, to whom he was married from 1941 to 1978. He married Libby Shulman Ely, with whom he had 4 stepchildren, in 1979.〔http://www.independent.co.uk/news/people/obituary-christian-anfinsen-1620834.html〕 His papers were donated to the National Library of Medicine by Libby Anfinsen between 1998 and 1999.〔(【引用サイトリンク】title=Christian Anfinsen Papers 1939-1999 (bulk 1964-1999) )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Christian B. Anfinsen」の詳細全文を読む スポンサード リンク
|